human FIG4 Over-expression AAV

Name 
AAV-h-FIG4
Cat No 
AAV-209027
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FIG4.

AAV-209027
AAV-h-FIG4

Ready-to-use AAV expressing Human FIG4 (FIG4 phosphoinositide 5-phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALS11; BTOP; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS
Description (Vector)
FIG4 belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Gene ID
9896
Gene Name (Vector)
FIG4 phosphoinositide 5-phosphatase
Gene Symbol
FIG4
HGNC ID
HGNC:16873
ORF Size (aa)
2724
ORF Size (bp)
2724 bp
RefSeq ID
NM_014845
RefSeq Synonyms
NM_014845, BC041338,
Species
human
UniGene ID
Hs.529959

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.