human FGF2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-208961
Availability:
3-5 weeks
Name:
AAV-h-FGF2
This is an AAV expressing Human FGF2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- FGF2
- Gene Name
- fibroblast growth factor 2
- Gene ID
- 2247
- Gene Synonyms
- BFGF; FGF-2; FGFB; HBGF-2
- ORF Size
- 867 bp
- RefSeq#
- BC166646
- Gene Description
- FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
- UniGene ID
- Hs.284244
- HGNC ID
- HGNC:3676
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