human FEZ1 Over-expression AAV

Name
AAV-h-FEZ1

Cat No
AAV-208919

Availability
4-5 weeks

This is an AAV expressing Human FEZ1.

AAV-208919

AAV-h-FEZ1

Ready-to-use AAV expressing Human FEZ1 (fasciculation and elongation protein zeta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

UNC-76

Description (Vector)

FEZ1 is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.

Gene ID

9638

Gene Name (Vector)

fasciculation and elongation protein zeta 1

Gene Symbol

FEZ1

HGNC ID

HGNC:3659

ORF Size (aa)

1179

ORF Size (bp)

1179 bp

RefSeq ID

NM_005103

RefSeq Synonyms

NM_022549, NM_005103, BC009545,

Species

human

UniGene ID

Hs.224008

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.