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human FCGR3B Over-expression AAV

Name 
AAV-h-FCGR3B
Cat No 
AAV-208865
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FCGR3B.

AAV-208865
AAV-h-FCGR3B

Ready-to-use AAV expressing Human FCGR3B (Fc fragment of IgG receptor IIIb). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD16b; CD16; CD16A; CD16b; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; fc-gamma RIII-beta; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb; igG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B
Description (eCommerce)
CD16 is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG), and acts as a monomer and can bind either monomeric or aggregated IgG. CD16 may function to capture immune complexes in the peripheral circulation, and several transcript variants encoding different isoforms have been found (provided by RefSeq).
Description (Vector)
FCGR3B is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
Gene ID
2215
Gene Name (eCommerce)
Fc fragment of IgG receptor IIIb
Gene Name (Vector)
Fc fragment of IgG receptor IIIb
Gene Symbol
FCGR3B
HGNC ID
HGNC:3620
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
702
ORF Size (bp)
702 bp
Protein Name (eCommerce)
Low affinity immunoglobulin gamma Fc region receptor III-B
RefSeq ID
NM_000570
RefSeq Synonyms
NM_001271037, NM_001271036, NM_001271035, NM_001244753, NM_000570, BC128562,
Research Areas
Immunology, Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
CD16 is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG), and acts as a monomer and can bind either monomeric or aggregated IgG. CD16 may function to capture immune complexes in the peripheral circulation, and several transcript variants encoding different isoforms have been found (provided by RefSeq).
UniGene ID
Hs.694258
UniProt ID (eCommerce)
O75015

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.