human FBXL6 Over-expression AAV

Name
AAV-h-FBXL6

Cat No
AAV-208765

Availability
4-5 weeks

This is an AAV expressing Human FBXL6.

AAV-208765

AAV-h-FBXL6

Ready-to-use AAV expressing Human FBXL6 (F-box and leucine rich repeat protein 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FBL6; FBL6A; PP14630

Description (Vector)

FBXL6 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.

Gene ID

26233

Gene Name (Vector)

F-box and leucine rich repeat protein 6

Gene Symbol

FBXL6

HGNC ID

HGNC:13603

ORF Size (aa)

1620

ORF Size (bp)

1620 bp

RefSeq ID

NM_012162

RefSeq Synonyms

NM_024555, NM_012162, BC033066,

Species

human

UniGene ID

Hs.12271

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.