human F9 Over-expression AAV

Name 
AAV-h-F9
Cat No 
AAV-208237
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human F9.

AAV-208237
AAV-h-F9

Ready-to-use AAV expressing Human F9 (coagulation factor IX). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
F9 p22; FIX; HEMB; P19; PTC; THPH8
Description (Vector)
F9 encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
Gene ID
2158
Gene Name (Vector)
coagulation factor IX
Gene Symbol
F9
HGNC ID
HGNC:3551
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_000133
RefSeq Synonyms
NM_001313913, NM_000133, BC109215, BC109214,
Species
human
UniGene ID
Hs.522798

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.