human EXOC7 Over-expression AAV

Name 
AAV-h-EXOC7
Cat No 
AAV-208181
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EXOC7.

AAV-208181
AAV-h-EXOC7

Ready-to-use AAV expressing Human EXOC7 (exocyst complex component 7). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2-5-3p; BLOM4; EX070; EXO70; Exo70p; EXOC1; exocyst complex component 7; exocyst complex component Exo70; YJL085W
Description (eCommerce)
Exo70 is a component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, Exo70 plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UPT5].
Description (Vector)
EXOC7 is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
Gene ID
23265
Gene Name (eCommerce)
exocyst complex component 7
Gene Name (Vector)
exocyst complex component 7
Gene Symbol
EXOC7
HGNC ID
HGNC:23214
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2208
ORF Size (bp)
2208 bp
Protein Name (eCommerce)
Exocyst complex component 7
RefSeq ID
NM_015219
RefSeq Synonyms
NM_015219, NM_001282314, NM_001282313, NM_001145299, NM_001145298, NM_001145297, NM_001013839, BC018466, BC015165, BC011045,
Research Areas
Insulin Signaling,Signal Transduction,Transport
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Exo70 is a component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, Exo70 plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UPT5].
UniGene ID
Hs.626313
UniProt ID (eCommerce)
Q9UPT5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.