human EN2 Over-expression AAV

Name
AAV-h-EN2

Cat No
AAV-207900

Availability
4-5 weeks

This is an AAV expressing Human EN2.

AAV-207900

AAV-h-EN2

Ready-to-use AAV expressing Human EN2 (engrailed homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Gene ID

2020

Gene Name (Vector)

engrailed homeobox 2

Gene Symbol

EN2

HGNC ID

HGNC:3343

ORF Size (aa)

1002

ORF Size (bp)

1002 bp

RefSeq ID

NM_001427

RefSeq Synonyms

NM_001427, BC104972, BC104970,

Species

human

UniGene ID

Hs.134989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.