human EMD Over-expression AAV

Name 
AAV-h-EMD
Cat No 
AAV-207871
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EMD.

AAV-207871
AAV-h-EMD

Ready-to-use AAV expressing Human EMD (emerin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDMD; emerin; LEM domain containing 5; LEMD5; STA
Description (eCommerce)
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene [taken from NCBI Entrez Gene (Gene ID: 2010)].
Description (Vector)
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Gene ID
2010
Gene Name (eCommerce)
emerin
Gene Name (Vector)
emerin
Gene Symbol
EMD
HGNC ID
HGNC:3331
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
765
ORF Size (bp)
765 bp
Protein Name (eCommerce)
Emerin
RefSeq ID
NM_000117
RefSeq Synonyms
NM_000117, BC000738,
Research Areas
Cardiology,Cardiomyopathy,Cardiovascular,Cell Cycle,Cytoskeleton,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene [taken from NCBI Entrez Gene (Gene ID: 2010)].
UniGene ID
Hs.522823
UniProt ID (eCommerce)
P50402

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.