human EIF3B Over-expression AAV

Name 
AAV-h-EIF3B
Cat No 
AAV-207732
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EIF3B.

AAV-207732
AAV-h-EIF3B

Ready-to-use AAV expressing Human EIF3B (eukaryotic translation initiation factor 3 subunit B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
eIF3 p110; eIF3 p116; eIF3b; eIF-3-eta; EIF3-ETA; EIF3-P110; EIF3-P116; EIF3S9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD); eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; hPrt1; PRT1; prt1 homolog
Description (eCommerce)
Eukaryotic initiation factor 3 subunit B (eIF3B) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3B is a conserved subunit and part of the functional core of eIF3. It bears a non-canonical RNA recognition motif (RRM) and interacts directly with the eIF3S1 subunit.
Gene ID
8662
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit B
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit B
Gene Symbol
EIF3B
HGNC ID
HGNC:3280
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2445
ORF Size (bp)
2445 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit B
RefSeq ID
NM_003751
RefSeq Synonyms
NM_003751, NM_001037283, BC110865, BC001173,
Research Areas
Gene Expression,Interleukin Signaling,Metabolism/Metabolic Process,mRNA Binding,RNA Binding,RNA Transport,Signal Transduction,Translational Control
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,signal_transduction,immunology,metabolism,genetics,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Eukaryotic initiation factor 3 subunit B (eIF3B) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3B is a conserved subunit and part of the functional core of eIF3. It bears a non-canonical RNA recognition motif (RRM) and interacts directly with the eIF3S1 subunit.
UniGene ID
Hs.371001
UniProt ID (eCommerce)
P55884

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.