human EDNRA Over-expression AAV

Name
AAV-h-EDNRA

Cat No
AAV-207569

Availability
4-5 weeks

This is an AAV expressing Human EDNRA.

AAV-207569

AAV-h-EDNRA

Ready-to-use AAV expressing Human EDNRA (endothelin receptor type A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR; MFDA

Description (Vector)

EDNRA encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Gene ID

1909

Gene Name (Vector)

endothelin receptor type A

Gene Symbol

EDNRA

HGNC ID

HGNC:3179

ORF Size (aa)

1284

ORF Size (bp)

1284 bp

RefSeq ID

NM_001957

RefSeq Synonyms

NM_001957, NM_001256283, NM_001166055, BC022511,

Species

human

UniGene ID

Hs.183713

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.