human EDAR Over-expression AAV

Name 
AAV-h-EDAR
Cat No 
AAV-207551
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EDAR.

AAV-207551
AAV-h-EDAR

Ready-to-use AAV expressing Human EDAR (ectodysplasin A receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DL; ECTD10A; ECTD10B; ED1R; ED3; ED5; EDA-A1R; EDA1R; EDA3; HRM1
Description (Vector)
EDAR encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Gene ID
10913
Gene Name (Vector)
ectodysplasin A receptor
Gene Symbol
EDAR
HGNC ID
HGNC:2895
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_022336
RefSeq Synonyms
NM_022336, BC093872, BC093870,
Species
human
UniGene ID
Hs.171971

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.