human DYNC1I2 Over-expression AAV

Name 
AAV-h-DYNC1I2
Cat No 
AAV-207461
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DYNC1I2.

AAV-207461
AAV-h-DYNC1I2

Ready-to-use AAV expressing Human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cytoplasmic dynein 1 intermediate chain 2; Cytoplasmic dynein intermediate chain 2; DH IC-2; DIC74; DNCI2; dynein intermediate chain 2, cytosolic; dynein, cytoplasmic, intermediate polypeptide 2; IC2; testis tissue sperm-binding protein Li 66n
Description (eCommerce)
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. DYNC1I2 is involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13409].
Gene ID
1781
Gene Name (eCommerce)
dynein cytoplasmic 1 intermediate chain 2
Gene Name (Vector)
dynein cytoplasmic 1 intermediate chain 2
Gene Symbol
DYNC1I2
HGNC ID
HGNC:2964
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
Protein Name (eCommerce)
Cytoplasmic dynein 1 intermediate chain 2
RefSeq ID
NM_001378
RefSeq Synonyms
NM_001378, NM_001320884, NM_001320883, NM_001320882, NM_001271790, NM_001271789, NM_001271788, NM_001271787, NM_001271786, NM_001271785, BC109375, BC091498, BC015038,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Cytoskeleton,Host-Virus Interactions,Immunology,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology,infectious_disease
Species
human
Target Sentence
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. DYNC1I2 is involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13409].
UniGene ID
Hs.546250
UniProt ID (eCommerce)
Q13409

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.