human DSN1 Over-expression AAV

Name
AAV-h-DSN1

Cat No
AAV-207356

Availability
4-5 weeks

This is an AAV expressing Human DSN1.

AAV-207356

AAV-h-DSN1

Ready-to-use AAV expressing Human DSN1 (DSN1 homolog, MIS12 kinetochore complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C20orf172; dJ469A13.2; hKNL-3; KNL3; MIS13

Description (Vector)

DSN1 encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.

Gene ID

79980

Gene Name (Vector)

DSN1 homolog, MIS12 kinetochore complex component

Gene Symbol

DSN1

HGNC ID

HGNC:16165

ORF Size (aa)

1071

ORF Size (bp)

1071 bp

RefSeq ID

NM_024918

RefSeq Synonyms

NM_024918, NM_001145318, NM_001145317, NM_001145316, NM_001145315, BC058899, BC026011,

Species

human

UniGene ID

Hs.632268

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.