human DPM2 Over-expression AAV

Name 
AAV-h-DPM2
Cat No 
AAV-207284
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DPM2.

AAV-207284
AAV-h-DPM2

Ready-to-use AAV expressing Human DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDG1U
Description (Vector)
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
Gene ID
8818
Gene Name (Vector)
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Gene Symbol
DPM2
HGNC ID
HGNC:3006
ORF Size (aa)
207
RefSeq ID
NM_003863
RefSeq Synonyms
NM_003863, BC107863, BC015374, BC015233,
Species
human
UniGene ID
Hs.108973

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AAV-h-DPM2

Cat No: AAV-207282

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.