human DKK3 Over-expression AAV

Name 
AAV-h-DKK3
Cat No 
AAV-207028
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DKK3.

AAV-207028
AAV-h-DKK3

Ready-to-use AAV expressing Human DKK3 (dickkopf WNT signaling pathway inhibitor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
REIC; RIG
Description (Vector)
DKK3 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
27122
Gene Name (Vector)
dickkopf WNT signaling pathway inhibitor 3
Gene Symbol
DKK3
HGNC ID
HGNC:2893
ORF Size (aa)
1053
ORF Size (bp)
1053 bp
RefSeq ID
NM_015881
RefSeq Synonyms
NM_015881, NM_013253, NM_001330220, NM_001018057, BC007660,
Species
human
UniGene ID
Hs.292156

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.