human DGCR2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-206911
Availability:
3-5 weeks
Name:
AAV-h-DGCR2
This is an AAV expressing Human DGCR2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DGCR2
- Gene Name
- DiGeorge syndrome critical region gene 2
- Gene ID
- 9993
- Gene Synonyms
- DGS-C; IDD; LAN; SEZ-12
- ORF Size
- 1653 bp
- RefSeq#
- BC040500
- Gene Description
- Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
- UniGene ID
- Hs.517357
- HGNC ID
- HGNC:2845
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