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human DCD Over-expression AAV

Name 
AAV-h-DCD
Cat No 
AAV-206640
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DCD.

AAV-206640
AAV-h-DCD

Ready-to-use AAV expressing Human DCD (dermcidin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIDD; DCD-1; DSEP; HCAP; PIF
Description (Vector)
DCD encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
Gene ID
117159
Gene Name (Vector)
dermcidin
Gene Symbol
DCD
HGNC ID
HGNC:14669
ORF Size (aa)
333
RefSeq ID
NM_053283
RefSeq Synonyms
NM_053283, NM_001300854, BC069108, BC062682,
Species
human
UniGene ID
Hs.350570

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.