human CXCL1 Over-expression AAV

Name
AAV-h-CXCL1

Cat No
AAV-206326

Availability
4-5 weeks

This is an AAV expressing Human CXCL1.

AAV-206326

AAV-h-CXCL1

Ready-to-use AAV expressing Human CXCL1 (C-X-C motif chemokine ligand 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1

Description (Vector)

CXCL1 encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Gene ID

2919

Gene Name (Vector)

C-X-C motif chemokine ligand 1

Gene Symbol

CXCL1

HGNC ID

HGNC:4602

ORF Size (aa)

324

RefSeq ID

NM_001511

RefSeq Synonyms

NM_001511, BC011976,

Species

human

UniGene ID

Hs.789

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.