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human CSTF2 Over-expression AAV

Name 
AAV-h-CSTF2
Cat No 
AAV-206193
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CSTF2.

AAV-206193
AAV-h-CSTF2

Ready-to-use AAV expressing Human CSTF2 (cleavage stimulation factor subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
betaCstF-64 variant 2; CF-1 64 kDa subunit; cleavage stimulation factor 64 kDa subunit; cleavage stimulation factor subunit 2; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; CSTF 64 kDa subunit; CstF-64
Description (eCommerce)
CSTF64 is the RNA-binding 64 kDa subunit of the cleavage stimulation factor (CstF). CstF is part of the polyadenylation machinery that adds adenylate residues to the 3’-ends of eukaryotic pre-mRNAs. In the CstF complex, CSTF64 interacts with CSTF1 (CSTF50), and CSTF3 (CSTF77).
Description (Vector)
CSTF2 encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
Gene ID
1478
Gene Name (eCommerce)
cleavage stimulation factor subunit 2
Gene Name (Vector)
cleavage stimulation factor subunit 2
Gene Symbol
CSTF2
HGNC ID
HGNC:2484
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
Protein Name (eCommerce)
Cleavage stimulation factor subunit 2
RefSeq ID
NM_001325
RefSeq Synonyms
NM_001325, NM_001306209, NM_001306206, BC017712,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CSTF64 is the RNA-binding 64 kDa subunit of the cleavage stimulation factor (CstF). CstF is part of the polyadenylation machinery that adds adenylate residues to the 3’-ends of eukaryotic pre-mRNAs. In the CstF complex, CSTF64 interacts with CSTF1 (CSTF50), and CSTF3 (CSTF77).
UniGene ID
Hs.132370
UniProt ID (eCommerce)
P33240

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.