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human CNOT10 Over-expression AAV

Name 
AAV-h-CNOT10
Cat No 
AAV-205605
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CNOT10.

AAV-205605
AAV-h-CNOT10

Ready-to-use AAV expressing Human CNOT10 (CCR4-NOT transcription complex subunit 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCR4-NOT transcription complex subunit 10
Description (eCommerce)
CCR4-NOT transcription complex subunit 10 (CNOT10) is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H9A5].
Gene ID
25904
Gene Name (eCommerce)
CCR4-NOT transcription complex subunit 10
Gene Name (Vector)
CCR4-NOT transcription complex subunit 10
Gene Symbol
CNOT10
HGNC ID
HGNC:23817
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2154
ORF Size (bp)
2154 bp
Protein Name (eCommerce)
CCR4-NOT transcription complex subunit 10
RefSeq ID
NM_015442
RefSeq Synonyms
NM_015442, NM_001256742, NM_001256741, BC002931, BC002928,
Research Areas
Gene Expression,RNA Processing,Transcription Factor/Regulator,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
CCR4-NOT transcription complex subunit 10 (CNOT10) is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H9A5].
UniGene ID
Hs.444851
UniProt ID (eCommerce)
Q9H9A5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.