human CLDN5 Over-expression AAV

Cat. No: AAV-205383

Availability: 3-5 weeks

Name: AAV-h-CLDN5

This is an AAV expressing Human CLDN5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CLDN5
Gene Name: claudin 5
Gene ID: 7122
Gene Synonyms: AWAL; BEC1; CPETRL1; TMVCF
ORF Size: 657 bp
RefSeq#: BC019290
Gene Description: CLDN5 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.505337
HGNC ID: HGNC:2047