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human CHRM2 Over-expression AAV

Name 
AAV-h-CHRM2
Cat No 
AAV-205198
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CHRM2.

AAV-205198
AAV-h-CHRM2

Ready-to-use AAV expressing Human CHRM2 (cholinergic receptor muscarinic 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HM2
Description (Vector)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Gene ID
1129
Gene Name (Vector)
cholinergic receptor muscarinic 2
Gene Symbol
CHRM2
HGNC ID
HGNC:1951
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_000739
RefSeq Synonyms
NM_001006632, NM_001006631, NM_001006630, NM_001006629, NM_001006628, NM_001006627, NM_001006626, NM_000739, BC106742, BC106741, BC095547,
Species
human
UniGene ID
Hs.535891

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.