human CHRFAM7A Over-expression AAV
This is an AAV expressing Human CHRFAM7A.
AAV-205192
AAV-h-CHRFAM7A
Ready-to-use AAV expressing Human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CHRNA7; CHRNA7-DR1; D-10
Description (Vector)
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Gene ID
89832
Gene Name (Vector)
CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
Gene Symbol
CHRFAM7A
HGNC ID
HGNC:15781
ORF Size (aa)
966
RefSeq ID
NM_139320
RefSeq Synonyms
NM_148911, NM_139320, BC101348, BC101347, BC101346, BC101345,
Species
human
UniGene ID
Hs.510853
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.