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human CGGBP1 Over-expression AAV

Name 
AAV-h-CGGBP1
Cat No 
AAV-205075
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CGGBP1.

AAV-205075
AAV-h-CGGBP1

Ready-to-use AAV expressing Human CGGBP1 (CGG triplet repeat binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
20 kDa CGG-binding protein; CGG triplet repeat-binding protein 1; CGG-binding protein 1; CGGBP; p20-CGG binding protein; p20-CGGBP; p20-CGGBP DNA-binding protein
Description (eCommerce)
CGG triplet repeat binding protein 1 (CGGBP1) binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. CGGBP1 may play a role in regulating FMR1 promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14789].
Description (Vector)
CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.(supplied by OMIM, Mar 2008)
Gene ID
8545
Gene Name (eCommerce)
CGG triplet repeat binding protein 1
Gene Name (Vector)
CGG triplet repeat binding protein 1
Gene Symbol
CGGBP1
HGNC ID
HGNC:1888
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
504
ORF Size (bp)
504 bp
Protein Name (eCommerce)
CGG triplet repeat-binding protein 1
RefSeq ID
NM_003663
RefSeq Synonyms
NM_003663, NM_001195308, NM_001008390, BC052980,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
CGG triplet repeat binding protein 1 (CGGBP1) binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. CGGBP1 may play a role in regulating FMR1 promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14789].
UniGene ID
Hs.444818
UniProt ID (eCommerce)
Q9UFW8

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.