human CFHR3 Over-expression AAV

Name 
AAV-h-CFHR3
Cat No 
AAV-205048
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CFHR3.

AAV-205048
AAV-h-CFHR3

Ready-to-use AAV expressing Human CFHR3 (complement factor H related 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CFHL3; DOWN16; FHR-3; FHR3; HLF4
Description (Vector)
CFHR3 is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
10878
Gene Name (Vector)
complement factor H related 3
Gene Symbol
CFHR3
HGNC ID
HGNC:16980
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_021023
RefSeq Synonyms
NM_021023, NM_001166624, BC070259, BC058009, BC020687,
Species
human
UniGene ID
Hs.709217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.