human CFC1 Over-expression AAV

Name
AAV-h-CFC1

Cat No
AAV-205037

Availability
4-5 weeks

This is an AAV expressing Human CFC1.

AAV-205037

AAV-h-CFC1

Ready-to-use AAV expressing Human CFC1 (cripto, FRL-1, cryptic family 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CFC1B; CRYPTIC; DTGA2; HTX2

Description (Vector)

CFC1 encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

55997

Gene Name (Vector)

cripto, FRL-1, cryptic family 1

Gene Symbol

CFC1

HGNC ID

HGNC:18292

ORF Size (aa)

672

ORF Size (bp)

672 bp

RefSeq ID

NM_032545

RefSeq Synonyms

NM_032545, NM_001270421, NM_001270420, BC146897, BC110080, BC074826, BC074825, BC069508,

Species

human

UniGene ID

Hs.595719

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.