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human CENPI Over-expression AAV

Name 
AAV-h-CENPI
Cat No 
AAV-204958
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CENPI.

AAV-204958
AAV-h-CENPI

Ready-to-use AAV expressing Human CENPI (centromere protein I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CENP-I; centromere protein I; follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; FSHPRH1; interphase centromere complex protein 19; leucine-rich primary response protein 1; LRPR1
Description (eCommerce)
Centromere protein I (CENP-I) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENP-I may be involved in incorporation of newly synthesized CENP-A into centromeres via its interaction with the CENPA-NAC complex. CENP-I is required for the localization of CENP-F, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. CENP-A is involved in the response of gonadal tissues to follicle-stimulating hormone [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92674].
Description (Vector)
The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.
Gene ID
2491
Gene Name (eCommerce)
centromere protein I
Gene Name (Vector)
centromere protein I
Gene Symbol
CENPI
HGNC ID
HGNC:3968
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
Protein Name (eCommerce)
Centromere protein I
RefSeq ID
NM_006733
RefSeq Synonyms
NM_006733, NM_001318523, NM_001318521, BC012462,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Centromere protein I (CENP-I) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENP-I may be involved in incorporation of newly synthesized CENP-A into centromeres via its interaction with the CENPA-NAC complex. CENP-I is required for the localization of CENP-F, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. CENP-A is involved in the response of gonadal tissues to follicle-stimulating hormone [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92674].
UniGene ID
Hs.348920
UniProt ID (eCommerce)
Q92674

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.