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human CDK2AP1 Over-expression AAV

Name 
AAV-h-CDK2AP1
Cat No 
AAV-204840
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CDK2AP1.

AAV-204840
AAV-h-CDK2AP1

Ready-to-use AAV expressing Human CDK2AP1 (cyclin dependent kinase 2 associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
doc-1; DOC1; DORC1; p12DOC-1; ST19
Description (Vector)
CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
8099
Gene Name (Vector)
cyclin dependent kinase 2 associated protein 1
Gene Symbol
CDK2AP1
HGNC ID
HGNC:14002
ORF Size (aa)
348
RefSeq ID
NM_004642
RefSeq Synonyms
NM_004642, NM_001270434, NM_001270433, BC034717,
Species
human
UniGene ID
Hs.433201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.