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human CDH2 Over-expression AAV

Name 
AAV-h-CDH2
Cat No 
AAV-204814
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CDH2.

AAV-204814
AAV-h-CDH2

Ready-to-use AAV expressing Human CDH2 (cadherin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; calcium-dependent adhesion protein, neuronal; CD antigen CD325; CD325; CDHN; CDw325; NCAD; N-cadherin; N-cadherin 1; neural cadherin
Description (eCommerce)
N-Cadherin, or Cadherin-2, is a classical cadherin and member of the cadherin superfamily. N-Cadherin is a calcium-dependent cell adhesion molecule that plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [taken from NCBI Entrez Gene (Gene ID: 1000)].
Description (Vector)
CDH2 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Gene ID
1000
Gene Name (eCommerce)
cadherin 2
Gene Name (Vector)
cadherin 2
Gene Symbol
CDH2
HGNC ID
HGNC:1759
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
Protein Name (eCommerce)
Cadherin-2
RefSeq ID
NM_001792
RefSeq Synonyms
NM_001792, NM_001308176, BC036470,
Research Areas
Axonogenesis,BDNF Signaling,Cardiology,Cardiomyopathy,Cardiovascular,EGFR Signaling,FGF Signaling,MAPK Signaling,Neurobiology,Neurodevelopment,Rho Signaling,Signal Transduction,Translational Control,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
N-Cadherin, or Cadherin-2, is a classical cadherin and member of the cadherin superfamily. N-Cadherin is a calcium-dependent cell adhesion molecule that plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [taken from NCBI Entrez Gene (Gene ID: 1000)].
UniGene ID
Hs.606106
UniProt ID (eCommerce)
P19022

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.