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human CDC40 Over-expression AAV

Name 
AAV-h-CDC40
Cat No 
AAV-204755
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CDC40.

AAV-204755
AAV-h-CDC40

Ready-to-use AAV expressing Human CDC40 (cell division cycle 40). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cell division cycle 40 homolog; EHB3; EH-binding protein 3; hPRP17; pre-mRNA splicing factor 17; pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRPF17
Description (eCommerce)
Cell division cycle 40 homolog (CDC40) is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression [taken from NCBI Entrez Gene (Gene ID: 51362)].
Description (Vector)
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Gene ID
51362
Gene Name (eCommerce)
cell division cycle 40
Gene Name (Vector)
cell division cycle 40
Gene Symbol
CDC40
HGNC ID
HGNC:17350
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1740
ORF Size (bp)
1740 bp
Protein Name (eCommerce)
Pre-mRNA-processing factor 17
RefSeq ID
NM_015891
RefSeq Synonyms
NM_015891, BC126114, BC117145,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,mRNA Transport,RNA Processing,RNA Transport,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Cell division cycle 40 homolog (CDC40) is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression [taken from NCBI Entrez Gene (Gene ID: 51362)].
UniGene ID
Hs.428147
UniProt ID (eCommerce)
O60508

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.