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human CD80 Over-expression AAV

Name 
AAV-h-CD80
Cat No 
AAV-204686
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CD80.

AAV-204686
AAV-h-CD80

Ready-to-use AAV expressing Human CD80 (CD80 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD antigen CD80; CD28LG; CD28LG1; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
Description (eCommerce)
CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P33681].
Description (Vector)
CD80 is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Gene ID
941
Gene Name (eCommerce)
CD80 molecule
Gene Name (Vector)
CD80 molecule
Gene Symbol
CD80
HGNC ID
HGNC:1700
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
867
ORF Size (bp)
867 bp
Protein Name (eCommerce)
T-lymphocyte activation antigen CD80
RefSeq ID
NM_005191
RefSeq Synonyms
NM_005191, BC042665,
Research Areas
B-cell Receptor Signaling,Cancer,Cardiology,Cardiovascular,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,GPCR Signaling,Host-Virus Interactions,Immunology,Innate Immunity,Interleukin Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,Toll-like Receptor Signaling
Research Areas (Faceted)
cancer,cardiovascular,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology
Species
human
Target Sentence
CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P33681].
UniGene ID
Hs.838
UniProt ID (eCommerce)
P33681

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.