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human CCNY Over-expression AAV

Name 
AAV-h-CCNY
Cat No 
AAV-204521
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CCNY.

AAV-204521
AAV-h-CCNY

Ready-to-use AAV expressing Human CCNY (cyclin Y). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C10orf9; CBCP1; CCNX; CFP1; cyclin box protein 1; cyclin fold protein 1; cyclin-box carrying protein 1; cyclin-X; cyclin-Y; cyc-Y
Description (eCommerce)
Cyclin Y is a recently identified member of the cyclin family of proteins which function as regulators of cyclin dependent kinases. It was identified as a protein that interacts with PFTK1, a factor that shares limited homology to CDKs, but functions as a CDK by regulating cell cycle progression and cell proliferation. The binding of cyclin Y to PFTK1 enhances PFTK1 kinase activity and influences its intracellular location.
Description (Vector)
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 (PubMed 18060517)).(supplied by OMIM, May 2009)
Gene ID
219771
Gene Name (eCommerce)
cyclin Y
Gene Name (Vector)
cyclin Y
Gene Symbol
CCNY
HGNC ID
HGNC:23354
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1026
ORF Size (bp)
1026 bp
Protein Name (eCommerce)
Cyclin-Y
RefSeq ID
NM_145012
RefSeq Synonyms
NM_181698, NM_145012, NM_001282854, NM_001282853, NM_001282852, BC143455, BC143450, BC104801, BC104773, BC094815,
Research Areas
Cell Cycle,Cell Division,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
Cyclin Y is a recently identified member of the cyclin family of proteins which function as regulators of cyclin dependent kinases. It was identified as a protein that interacts with PFTK1, a factor that shares limited homology to CDKs, but functions as a CDK by regulating cell cycle progression and cell proliferation. The binding of cyclin Y to PFTK1 enhances PFTK1 kinase activity and influences its intracellular location.
UniGene ID
Hs.714184
UniProt ID (eCommerce)
Q8ND76

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.