human MCU Over-expression AAV
This is an AAV expressing Human MCU.
AAV-204228
AAV-h-MCU
Ready-to-use AAV expressing Human MCU (mitochondrial calcium uniporter). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C10orf42;calcium uniporter protein, mitochondrial;CCDC109A;coiled-coil domain-containing protein 109A;HsMCU
Description (eCommerce)
MCU is a channel-forming and calcium-conducting subunit of the mitochondrial inner membrane calcium uniporter complex (uniplex), which mediates calcium uptake into the mitochondrial matrix. MCU is involved in several processes, including cellular response to calcium ion starvation, positive regulation of mitochondrial calcium ion concentration, and positive regulation of mitochondrial fission. [taken from NCBI Entrez Gene (Gene ID: 90550)].
Description (Vector)
MCU encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.
Gene ID
90550
Gene Name (eCommerce)
mitochondrial calcium uniporter
Gene Name (Vector)
mitochondrial calcium uniporter
Gene Symbol
MCU
HGNC ID
HGNC:23526
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
Protein Name (eCommerce)
Calcium uniporter protein, mitochondrial
RefSeq ID
NM_138357
RefSeq Synonyms
NM_138357, NM_001270680, NM_001270679, BC034235,
Research Areas (Faceted)
cell_biology
Species
human
UniGene ID
Hs.591366
UniProt ID (eCommerce)
Q8NE86
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.