human CAPNS1 Over-expression AAV

Name
AAV-h-CAPNS1

Cat No
AAV-204054

Availability
4-5 weeks

This is an AAV expressing Human CAPNS1.

AAV-204054

AAV-h-CAPNS1

Ready-to-use AAV expressing Human CAPNS1 (calpain small subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1

Description (Vector)

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Gene ID

826

Gene Name (Vector)

calpain small subunit 1

Gene Symbol

CAPNS1

HGNC ID

HGNC:1481

ORF Size (aa)

969

ORF Size (bp)

969 bp

RefSeq ID

NM_001749

RefSeq Synonyms

NM_001749, NM_001302633, NM_001302632, NM_001003962, BC064998, BC023643, BC021933, BC018931, BC017308, BC011903, BC007779, BC000592,

Species

human

UniGene ID

Hs.515371

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.