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human C8G Over-expression AAV

Name 
AAV-h-C8G
Cat No 
AAV-203714
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human C8G.

AAV-203714
AAV-h-C8G

Ready-to-use AAV expressing Human C8G (complement C8 gamma chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C8C
Description (Vector)
C8G belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Gene ID
733
Gene Name (Vector)
complement C8 gamma chain
Gene Symbol
C8G
HGNC ID
HGNC:1354
ORF Size (aa)
609
ORF Size (bp)
609 bp
RefSeq ID
NM_000606
RefSeq Synonyms
NM_000606, BC113626, BC113624,
Species
human
UniGene ID
Hs.1285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.