human C6ORF108 Over-expression AAV

Name 
AAV-h-C6ORF108
Cat No 
AAV-203546
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DNPH1.

AAV-203546
AAV-h-C6ORF108

Ready-to-use AAV expressing Human DNPH1 (2′-deoxynucleoside 5′-phosphate N-hydrolase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2'-deoxynucleoside 5'-phosphate N-hydrolase 1; C6orf108; c-Myc-responsive protein RCL; deoxyribonucleoside 5'-monophosphate N-glycosidase; dJ330M21.3; putative c-Myc-responsive; RCL
Description (eCommerce)
RCL catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43598].
Description (Vector)
C6orf108 was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described.
Gene ID
10591
Gene Name (eCommerce)
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Gene Name (Vector)
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Gene Symbol
DNPH1
HGNC ID
HGNC:21218
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
525
ORF Size (bp)
525 bp
Protein Name (eCommerce)
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
RefSeq ID
NM_006443
RefSeq Synonyms
NM_199184, NM_006443, BC011683,
Research Areas
Cell Biology,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
RCL catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43598].
UniGene ID
Hs.109752
UniProt ID (eCommerce)
O43598

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.