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human C4BPA Over-expression AAV

Name 
AAV-h-C4BPA
Cat No 
AAV-203440
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human C4BPA.

AAV-203440
AAV-h-C4BPA

Ready-to-use AAV expressing Human C4BPA (complement component 4 binding protein alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C4BP; PRP
Description (Vector)
C4BPA encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
Gene ID
722
Gene Name (Vector)
complement component 4 binding protein alpha
Gene Symbol
C4BPA
HGNC ID
HGNC:1325
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
RefSeq ID
NM_000715
RefSeq Synonyms
NM_000715, BC022312,
Species
human
UniGene ID
Hs.1012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.