human BRP44L Over-expression AAV

Name 
AAV-h-BRP44L
Cat No 
AAV-202277
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MPC1.

AAV-202277
AAV-h-BRP44L

Ready-to-use AAV expressing Human MPC1 (mitochondrial pyruvate carrier 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BRP44L; CGI-129; dJ68L15.3; MPYCD
Description (Vector)
MPC1 is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
Gene ID
51660
Gene Name (Vector)
mitochondrial pyruvate carrier 1
Gene Symbol
MPC1
HGNC ID
HGNC:21606
ORF Size (aa)
330
RefSeq ID
NM_016098
RefSeq Synonyms
NM_016098, NM_001270879, BC000810,
Species
human
UniGene ID
Hs.172755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.