human BOLA2 Over-expression AAV

Name
AAV-h-BOLA2

Cat No
AAV-202223

Availability
4-5 weeks

This is an AAV expressing Human BOLA2.

AAV-202223

AAV-h-BOLA2

Ready-to-use AAV expressing Human BOLA2 (bolA family member 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bolA homolog 2; BOLA2A; BOLA2B; bolA-like protein 2; BolA-like protein 2 member A; My016

Description (eCommerce)

BOLA2 acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts together with the monothiol glutaredoxin GLRX3. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3K6].

Description (Vector)

BOLA2 is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. BOLA2 encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation.

Gene ID

552900

Gene Name (eCommerce)

bolA family member 2

Gene Name (Vector)

bolA family member 2

Gene Symbol

BOLA2

HGNC ID

HGNC:29488

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

375

ORF Size (bp)

375 bp

Protein Name (eCommerce)

BolA-like protein 2

RefSeq ID

NM_001031827

RefSeq Synonyms

NM_001320579, NM_001031827, BC144688, BC130403, BC130401, BC062756, BC022832,

Research Areas

Interleukin Signaling

Research Areas (Faceted)

signal_transduction,immunology

Species

human

Target Sentence

BOLA2 acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts together with the monothiol glutaredoxin GLRX3. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3K6].

UniGene ID

Hs.655267

UniProt ID (eCommerce)

Q9H3K6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.