human BLVRB Over-expression AAV

Name
AAV-h-BLVRB

Cat No
AAV-202174

Availability
4-5 weeks

This is an AAV expressing Human BLVRB.

AAV-202174

AAV-h-BLVRB

Ready-to-use AAV expressing Human BLVRB (biliverdin reductase B). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Biliverdin reductase B; biliverdin-IX beta-reductase; BVRB; BVR-B; epididymis secretory protein Li 10; flavin reductase (NADPH); FLR; FR; GHBP; green heme-binding protein; HEL-S-10; NADPH; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U, member 1

Description (eCommerce)

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24) [taken from NCBI Entrez Gene (Gene ID: 645)].

Description (Vector)

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).(supplied by OMIM, Jul 2009)

Gene ID

645

Gene Name (eCommerce)

biliverdin reductase B

Gene Name (Vector)

biliverdin reductase B

Gene Symbol

BLVRB

HGNC ID

HGNC:1063

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

621

Protein Name (eCommerce)

Flavin reductase

RefSeq ID

NM_000713

RefSeq Synonyms

NM_000713, BC109371,

Research Areas

Immunology,Interleukin Signaling,Metabolism/Metabolic Process

Research Areas (Faceted)

cell_biology,immunology,metabolism,signal_transduction

Species

human

Target Sentence

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24) [taken from NCBI Entrez Gene (Gene ID: 645)].

UniGene ID

Hs.515785

UniProt ID (eCommerce)

P30043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.