human BHMT2 Over-expression AAV

Name 
AAV-h-BHMT2
Cat No 
AAV-202133
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BHMT2.

AAV-202133
AAV-h-BHMT2

Ready-to-use AAV expressing Human BHMT2 (betaine–homocysteine S-methyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
23743
Gene Name (Vector)
betaine--homocysteine S-methyltransferase 2
Gene Symbol
BHMT2
HGNC ID
HGNC:1048
ORF Size (aa)
1092
ORF Size (bp)
1092 bp
RefSeq ID
NM_017614
RefSeq Synonyms
NM_017614, NM_001178005, BC020665,
Species
human
UniGene ID
Hs.114172

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.