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human B4GALT6 Over-expression AAV

Name 
AAV-h-B4GALT6
Cat No 
AAV-201916
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human B4GALT6.

AAV-201916
AAV-h-B4GALT6

Ready-to-use AAV expressing Human B4GALT6 (beta-1,4-galactosyltransferase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B4Gal-T6; beta4Gal-T6
Description (Vector)
B4GALT6 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.
Gene ID
9331
Gene Name (Vector)
beta-1,4-galactosyltransferase 6
Gene Symbol
B4GALT6
HGNC ID
HGNC:929
ORF Size (aa)
1149
ORF Size (bp)
1149 bp
RefSeq ID
NM_004775
RefSeq Synonyms
NM_004775, NM_001330570, BC074884, BC074835, BC069642, BC069620,
Species
human
UniGene ID
Hs.591063

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.