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human ATXN2L Over-expression AAV

Name 
AAV-h-ATXN2L
Cat No 
AAV-201814
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATXN2L.

AAV-201814
AAV-h-ATXN2L

Ready-to-use AAV expressing Human ATXN2L (ataxin 2 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A2D; A2LG; A2LP; A2RP; ataxin 2 related protein; ataxin-2 domain protein; ataxin-2-like protein; Ataxin-2-related protein
Description (eCommerce)
Ataxin 2-like (ATXN2L) is related to the spinocerebellar ataxia (SCA) family of proteins associated with a group of neurodegenerative disorders characterized by progressive ataxia and cerebellar dysfunction. The specific function of ATXN2L has not been described.
Description (Vector)
ATXN2L encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.
Gene ID
11273
Gene Name (eCommerce)
ataxin 2 like
Gene Name (Vector)
ataxin 2 like
Gene Symbol
ATXN2L
HGNC ID
HGNC:31326
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3135
ORF Size (bp)
3135 bp
Protein Name (eCommerce)
Ataxin-2-like protein
RefSeq ID
NM_007245
RefSeq Synonyms
NM_148416, NM_148415, NM_148414, NM_145714, NM_017492, NM_007245, NM_001308230, BC136584, BC082760,
Research Areas
Neurobiology,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,neurobiology,transcription_translation
Species
human
Target Sentence
Ataxin 2-like (ATXN2L) is related to the spinocerebellar ataxia (SCA) family of proteins associated with a group of neurodegenerative disorders characterized by progressive ataxia and cerebellar dysfunction. The specific function of ATXN2L has not been described.
UniGene ID
Hs.460499
UniProt ID (eCommerce)
Q8WWM7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.