human ATP6V1G3 Over-expression AAV

Name 
AAV-h-ATP6V1G3
Cat No 
AAV-201774
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATP6V1G3.

AAV-201774
AAV-h-ATP6V1G3

Ready-to-use AAV expressing Human ATP6V1G3 (ATPase H+ transporting V1 subunit G3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATP6G3; Vma10
Description (Vector)
ATP6V1G3 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. ATP6V1G3 encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.
Gene ID
127124
Gene Name (Vector)
ATPase H+ transporting V1 subunit G3
Gene Symbol
ATP6V1G3
HGNC ID
HGNC:18265
ORF Size (aa)
375
ORF Size (bp)
375 bp
RefSeq ID
NM_133262
RefSeq Synonyms
NM_133326, NM_133262, NM_001320218, BC101131, BC101130, BC101129,
Species
human
UniGene ID
Hs.127743

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.