human ATP1B4 Over-expression AAV

Name
AAV-h-ATP1B4

Cat No
AAV-201689

Availability
4-5 weeks

This is an AAV expressing Human ATP1B4.

AAV-201689

AAV-h-ATP1B4

Ready-to-use AAV expressing Human ATP1B4 (ATPase Na+/K+ transporting family member beta 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ATP1B4 has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

23439

Gene Name (Vector)

ATPase Na+/K+ transporting family member beta 4

Gene Symbol

ATP1B4

ORF Size (aa)

945

ORF Size (bp)

945 bp

RefSeq ID

NM_012069

RefSeq Synonyms

NM_012069, NM_001142447, BC143407, BC143406, BC143404, BC117227,

Species

human

UniGene ID

Hs.662608

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.