human ATG12 Over-expression AAV

Name
AAV-h-ATG12

Cat No
AAV-201633

Availability
4-5 weeks

This is an AAV expressing Human ATG12.

AAV-201633

AAV-h-ATG12

Ready-to-use AAV expressing Human ATG12 (autophagy related 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APG12; APG12L; FBR93; HAPG12

Description (Vector)

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 (PubMed 9852036)).(supplied by OMIM, Mar 2008)

Gene ID

9140

Gene Name (Vector)

autophagy related 12

Gene Symbol

ATG12

HGNC ID

HGNC:588

ORF Size (aa)

564

ORF Size (bp)

564 bp

RefSeq ID

NM_004707

RefSeq Synonyms

NM_004707, NM_001277783, BC012266,

Species

human

UniGene ID

Hs.264482

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.