human ATF4 Over-expression AAV

Name 
AAV-h-ATF4
Cat No 
AAV-201618
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATF4.

AAV-201618
AAV-h-ATF4

Ready-to-use AAV expressing Human ATF4 (activating transcription factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CREB-2; CREB2; TAXREB67; TXREB
Description (Vector)
ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
Gene ID
468
Gene Name (Vector)
activating transcription factor 4
Gene Symbol
ATF4
HGNC ID
HGNC:786
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_001675
RefSeq Synonyms
NM_182810, NM_001675, BC073990, BC073754, BC044895, BC024775, BC022088, BC016855, BC011994, BC008090,
Species
human
UniGene ID
Hs.496487

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.