human ASB14 Over-expression AAV

Name
AAV-h-ASB14

Cat No
AAV-201522

Availability
4-5 weeks

This is an AAV expressing Human ASB14.

AAV-201522

AAV-h-ASB14

Ready-to-use AAV expressing Human ASB14 (ankyrin repeat and SOCS box containing 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ASB14 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

142686

Gene Name (Vector)

ankyrin repeat and SOCS box containing 14

Gene Symbol

ASB14

HGNC ID

HGNC:19766

ORF Size (aa)

690

ORF Size (bp)

690 bp

RefSeq ID

NM_130387

RefSeq Synonyms

NM_130387, NM_001142733, BC114953,

Species

human

UniGene ID

Hs.703052

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.