human ART4 Over-expression AAV

Name
AAV-h-ART4

Cat No
AAV-201501

Availability
4-5 weeks

This is an AAV expressing Human ART4.

AAV-201501

AAV-h-ART4

Ready-to-use AAV expressing Human ART4 (ADP-ribosyltransferase 4 (Dombrock blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARTC4; CD297; DO; DOK1

Description (Vector)

ART4 encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known.

Gene ID

420

Gene Name (Vector)

ADP-ribosyltransferase 4 (Dombrock blood group)

Gene Symbol

ART4

HGNC ID

HGNC:726

ORF Size (aa)

945

ORF Size (bp)

945 bp

RefSeq ID

NM_021071

RefSeq Synonyms

NM_021071, BC074727,

Species

human

UniGene ID

Hs.668803

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.